Month: August 2016

A recently published study sought to determine which of two flu vaccines would provide better community protection when administered in children. Influenza, commonly called the flu, is a contagious respiratory illness caused by the influenza virus. The elderly, pregnant women, people with health conditions, and children are among those who are more likely to acquire
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August 31, 2016, by NCI Staff Metastatic melanoma cells. Credit: National Cancer Institute A pilot study by NCI researchers suggests that tumor DNA circulating in the blood of patients with cancer might be a biological marker for determining, soon after the treatment has started, whether a form of immunotherapy is likely to work for a
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August 29, 2016, by NCI Staff NCI’s cancer information products are constantly evolving and growing, so periodically we provide updates on new content of interest to the cancer community. Smokefree.gov Redesigned The Smokefree.gov website has undergone a major redesign. The site also features new and updated content, including a Pregnancy and Smoking Infographic and the
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The number of nasal allergies is increasing over time, however, asthma symptoms among adults tend to remain stable. Although past research investigating the prevalence of asthma and allergies among adult populations is relatively scant, information that does exist tends to suggest two trends: first, that asthma symptoms tend to remain stable over time, and second,
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August 24, 2016, by NCI Staff On August 5, the FDA approved the immunotherapy drug pembrolizumab for some patients with head and neck cancer. Credit: Terese Winslow UPDATE: On July 24, 2017, Merck reported that the phase III clinical trial launched to confirm the clinical benefit of pembrolizumab in patients with head and neck cancer,
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August 22, 2016, by NCI Staff An electron micrograph showing Salmonella typhimurium (red) infecting human cells (yellow). Credit: NIAID Biodefense Image Library Researchers at the University of Massachusetts Medical School have designed a nanoparticle that mimics the bacterium Salmonella and may help to counteract a major mechanism of chemotherapy resistance. Working with mouse models of
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A recent study showed that influenza vaccine reduces stroke and heart failure-related complications in adult diabetic patients, a high-risk group for influenza-related complications. This study further justifies the strong recommendation for influenza vaccination in older adults with chronic illnesses. There is a lack of good clinical studies that measure the effectiveness of influenza vaccination in
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A Dutch research group compared the effect of methylphenidate hydrochloride in adults and in children with ADHD, and found that the drug induced alterations in the brain blood flow of children, but not in adults. Methylphenidate hydrochloride, sold under the brand names like Ritalin, is a commonly used medication for attention-deficit hyperactivity disorder (ADHD). It
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August 5, 2016, by NCI Staff A cancer cell (white) being attacked by two immune cells (red). Credit: National Cancer Institute For many patients with melanoma whose tumors shrink after treatment with a class of immunotherapy drugs called checkpoint inhibitors, their tumors eventually grow back despite continued treatment. A new study has identified genetic mechanisms
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August 1, 2016, by NCI Staff Fluorescence microscopy image showing P-selectin–targeting nanoparticles penetrating lab-grown tumor tissue. Credit: Memorial Sloan Kettering Cancer Center/Yosi Shamay, Ph.D., and Daniel Heller, Ph.D. In a set of studies in mice bearing human tumors, nanoparticles designed to bind to a protein called P-selectin successfully delivered both chemotherapy drugs and targeted therapies
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Abstract β-Cell proliferation and expansion during pregnancy are crucial for maintaining euglycemia in response to increased metabolic demands placed on the mother. Prolactin and placental lactogen signal through the prolactin receptor (PRLR) and contribute to adaptive β-cell responses in pregnancy; however, the in vivo requirement for PRLR signaling specifically in maternal β-cell adaptations remains unknown.
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