Month: July 2017

WASHINGTON – Marva Moxey-Mims, M.D., a leading expert in chronic kidney disease and glomerular disease who has conceptualized and overseen multicenter clinical studies aimed at improving chronic kidney disease treatment, has been named Chief of Pediatric Nephrology at Children’s National Health System.  Dr. Moxey-Mims comes to Children’s National from the National Institute of Diabetes and Digestive
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A recent study explored the antibacterial effects of modified forms of vancomycin on antibiotic-resistant bacteria. The results suggest C1-aminomethylene vancomycin may be an effective agent against methicillin-resistant Staphylococcus aureus (MRSA) and other antibiotic-resistant bacteria. The ability of bacterial strains to acquire resistance to antibiotics faster than antibacterial therapies can be developed is of growing concern.
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A recent systematic review and meta-analysis revealed a lack of association between incretin based drugs and mortality in patients with type II diabetes. Type II diabetes mellitus is characterized by a lack of insulin sensitivity and elevated blood sugar. Patients with diabetes are at higher risk of cardiovascular disease, nephropathy, neuropathy, and retinopathy. Current treatment
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WASHINGTON – (July 26, 2017) – The National Capital Consortium for Pediatric Device Innovation (NCC-PDI) is now accepting proposals for medical devices that address a significant yet unmet pediatric need. This year, up to six innovations will be awarded up to $50,000 each during the pediatric medical device pitch competition on Sunday, Sept. 24, 2017
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WASHINGTON – Because obesity affects one in six U.S. children and adolescents, there is a pressing need to identify the subset of overweight or obese kids at the highest risk of developing cardiovascular and metabolic complications and to direct interventions to them. Since frameworks used to identify adults at heightened risk for such complications are a
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Polymeric micelles are an important class of targeted drug delivery systems that act as carriers of chemotherapeutic agents. A recent review summarized the research being carried out in the development and use of polymeric micelles and micelle-forming drug-polymer conjugates for cancer therapy. A common problem in cancer treatment is the untargeted delivery of highly toxic
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  If you’re among the one in four people who pay for a gym membership but hasn’t exercised for six months (go on, own up) or one of the 36 per cent who have recently cancelled their membership, it’s time to look beyond the gym for shape-up motivation. And this summer, you can find inspiration
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Parent-based treatment (PBT) programs and family-based treatment (FBT) programs are similarly effective for child weight loss. Moreover, PBT is also effective for parent weight loss and energy intake, in addition to improving physical activity for both child and parent. Since one-third of American children are classified as obese or overweight, effective treatment programs are required
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July 25, 2017, by NCI Staff Credit: Christaras A, CC BY 2.5 On July 12, the Food and Drug Administration (FDA) changed its accelerated approval of blinatumomab (Blincyto®) for some patients with acute lymphoblastic leukemia (ALL) to a full approval and expanded the approved indications for its use. A type of immunotherapy known as a
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A recent study examined whether diet during pregnancy influences fat mass and adiposity in newborns. Many studies have reported links between maternal diet and birth outcomes and weight, indicating that maternal health and nutritional status play a key role in the future health of offspring. Diet during pregnancy has been associated with newborn adiposity and
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Researchers from Duke University in North Carolina produced pathogen-resistant crops without compromising the plant’s yield and fitness.   Plants are commonly attacked by microbial, viral or fungal pathogens. Improving crop production involves the applications of pesticides. In recent years, genetically modified pathogen-resistant crops that express a high level of immune proteins have been produced. One
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Hypertension is a predominant risk factor for stroke and cardiovascular disease. A meta-analysis found a significant inverse relationship between dietary intake of magnesium and risk of hypertension.   Hypertension, also known as high blood pressure, is a risk factor for several major causes of death including stroke and cardiovascular disease. About 29.6% of U.S. adults
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Studies have found that undernourished children are less physically active than well-nourished children. Researchers investigated the effects of lipid-based nutrients supplements (LNS) on the physical activity levels of children born to Malawian mothers and found that LNS does not increase physical activity in Malawian toddlers. Poor dietary intake and malnutrition are issues prevalent in developing
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A study published in the Journal of Nutrition shows that replacement of refined carbohydrates with a combination of Egg protein and unsaturated fats increases insulin sensitivity and lowers triglycerides in obese adults with elevated triglyceride levels. Hypertriglyceridemia, defined as a fasting plasma Triglyceride (TG) concentration of more than 150 mg/dL, is a common condition in
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 An expert panel has published guidelines for treatment of Pediatric Acute Onset Neuropsychiatric Syndrome (PANS) and a subset of patients diagnosed with PAN Disorder Associated with Streptococcal Infection (PANDAS). The syndrome of sudden onset obsessive compulsive disorder and/or severe eating restrictions, and associated characteristic cognitive, behavioral or neurological symptoms, was first identified in the l990s
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July 21, 2017, by NCI Staff The DigniCap Scalp Cooling System. Credit: Yon Sim/Dignitana The Food and Drug Administration (FDA) has cleared a cooling cap—a device designed to reduce hair loss during chemotherapy—for use by patients with any kind of solid tumor. FDA initially cleared the device, the DigniCap® Scalp Cooling System, for patients with
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Depression and anxiety are often prevalent in patients with chronic obstructive pulmonary disease (COPD), but these patients do not often seek traditional therapy. A recent study reports that telephone-based cognitive behavioral therapy significantly improved symptoms of depression in COPD patients after an eight-week telephone program. Chronic obstructive pulmonary disease (COPD) is a well-known disease affecting
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