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THURSDAY, March 10, 2016 (HealthDay News) — Most people appreciate the value of a good night’s sleep. But a new review has put a dollar amount on untreated insomnia in the United States, and found that it costs about $100 billion a year. The researchers said that providing drug and behavioral therapies for untreated insomnia
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March 7, 2016, by I. Lubensky, R. Chauqui, and J. Demchok Credit: National Cancer Institute Human biospecimens, as any cancer researcher will tell you, are a foundational resource in basic and clinical cancer research. And with the launch last year of President Obama’s Precision Medicine Initiative and his announcement in January about the launch of
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March 1, 2016, by NCI Staff Determining breast cancer risk: The discovery of BRCA1 and BRCA2 gene mutations improved screening and treatment decisions for breast and ovarian cancers. Testing for genetic mutations strongly associated with an increased breast cancer risk has risen dramatically among women younger than age 40 who are diagnosed with the disease,
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February 26, 2016, by NCI Staff Credit: National Cancer Institute Patients who miss radiation therapy sessions during cancer treatment have an increased risk of their disease returning, even if they eventually complete their course of radiation treatment, according to a new study. The magnitude of the effect was higher than the researchers anticipated, which they
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February 24, 2016, by NCI Staff Zebrafish in the laboratory of Leonard Zon, M.D. Credit: Boston Children’s Hospital / Leonard Zon, M.D. Researchers have created a model of cancer in zebrafish that allows them to capture live images of tumors forming and growing, in some cases from a single cell. Using the model, the researchers
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February 22, 2016, by NCI Staff Anatomy of the inside of the brain. Researchers have identified a genetic rearrangement that may drive the development of a rare benign brain tumor in children. The rearrangement, which causes parts of two genes to fuse, may spur the growth of tumors through three distinct biological mechanisms simultaneously, the
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February 19, 2016, by NCI Staff NCI’s SEER program recently updated The Status of Cancer, in their Did You Know? video series. Many other new resources are available from NCI. NCI constantly publishes new information on its websites, so periodically we provide updates on new content of interest to the cancer community. New Videos Did
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February 17, 2016, by Warren Kibbe, Ph.D. The Titan supercomputer at the U.S. Oak Ridge National Laboratory in Tennessee will be one of several supercomputers used in the NCI-DoE National Strategic Computing Initiative. Credit: Oak Ridge National Laboratory, U.S. Department of Energy Imagine the concentrated power of more than one million laptops working to screen
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February 12, 2016, by NCI Staff Three images of a patient with an HPV-positive oropharyngeal tumor (large arrow) that has spread to a nearby lymph node (small arrow). Credit: Oncology/UBM Medica www.theoncologyjournal.com In a new study, researchers have confirmed that infection with human papillomavirus (HPV) 16 precedes the development of some head and neck cancers.
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February 11, 2016, by NCI Staff By inhibiting the formation of microtublules (green), eribulin disrupts mitosis, a type of cell division, in tumor cells. Credit: Wikimedia Commons / Afunguy The Food and Drug Administration (FDA) approved eribulin mesylate (Halaven®) on January 28 for some patients with liposarcoma. The approval is for patients whose cancers are advanced
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February 10, 2016, by Douglas R. Lowy, M.D. Vice President Biden addresses the first meeting of the Cancer Moonshot Task Force. Credit: White House / Pete Souza Yesterday, the White House released the President’s fiscal year (FY) 2017 Budget Request, which includes $680 million of additional funding for NCI to support the cancer research initiative
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When the world quiets down at night, any little sound—like a creaky pipe, or a passing car—can seem earsplitting. But the solution to your less-than-silent nights may actually be more noise. “White noise machines decrease distraction by covering up noises that could keep you awake,” explains Carl Brazil, MD, the director of the Division of
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February 8, 2016, by NCI Staff An obese mouse (left) and a mouse of normal weight (right). Credit: Wikimedia Commons Researchers have identified a biological mechanism that may help explain a longstanding association between obesity and an increased risk of colorectal cancer in humans. In mice, the researchers found, the excess intake of calories reduced
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February 5, 2016, by NCI Staff Credit: National Cancer Institute Many women cancer survivors have problems with mobility and other physical functioning as a result of persistent peripheral neuropathy caused by chemotherapy treatment, according to a new study. The problems with physical functioning were associated with a substantial increase in the women’s risk for injurious
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February 2, 2016, by NCI Staff Noel Brewer, Ph.D. Credit: UNC Lineberger Comprehensive Cancer Center Last week, all 69 NCI-Designated Cancer Centers released a consensus statement on human papillomavirus (HPV) vaccination in the United States. The statement describes the continued low rates of HPV vaccination as “a serious public health threat,” recommends that parents have their children
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February 1, 2016, by Barbara Conley, M.D. In August 2015, NCI and the ECOG-ACRIN Cancer Research Group launched NCI-MATCH, the largest, first-of-its-kind precision medicine cancer clinical trial to date. As the trial has progressed, we felt it was a good time to bring the cancer community up to date on the status of NCI-MATCH and,
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January 29, 2016, by NCI Staff Two types of gold nanoparticles spiked with spherical nucleic acids. Researchers are testing these nanoparticles as cancer therapies and diagnostic tools. Credit: National Cancer Institute NCI recently released the Cancer Nanotechnology Plan 2015. In this interview, Piotr Grodzinski, Ph.D., director of NCI’s Office of Cancer Nanotechnology Research, discusses the
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January 28, 2016, by NCI Staff The Preparatory Education About Clinical Trials (PRE-ACT) program includes targeted video clips that address patients’ specific concerns and knowledge gaps. Credit: American Society of Clinical Oncology Educating patients with cancer about clinical trials prior to their first visit with their oncologist can improve their ability to make decisions about
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January 25, 2016, by NCI Staff Mutant versions of the p53 tumor suppressor protein can clump together, stopping them from functioning. Treatment with ReACp53 can prevent this aggregation and restore p53’s function. Researchers have developed a new approach for treating tumors that express mutant versions of the p53 protein, which are present in more than
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January 21, 2016, by Douglas R. Lowy, M.D. President Obama has tapped Vice President Biden to lead a major new cancer research initiative. Credit: The White House As many in the cancer community are aware by now, during his State of the Union address to Congress last week, President Obama gave a strong endorsement of Vice
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January 19, 2016, by NCI Staff A dividing lung cancer cell. Credit: National Institutes of Health The Food and Drug Administration (FDA) approved alectinib (Alecensa®) on December 11, 2015, for some patients with metastatic non-small cell lung cancer (NSCLC) with mutations in the ALK gene. The agency granted an accelerated approval for alectinib for patients whose cancer
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January 15, 2016, by NCI Staff Acalabrutinib (ACP-196) targets BTK, a key switch in a signaling pathway required for the growth and survival of chronic lymphocytic leukemia cells. Credit: Adrian Wiestner, M.D., NHLBI Reports from two early-stage trials of new oral drugs provide hope for patients with high-risk chronic lymphocytic leukemia (CLL) that has returned
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Signs of a toxic relationship are sometimes easy to spot—blatant infidelity or physical violence, for example. But there can often be more subtle signs that something’s just not right between you and your partner—or between you and a close friend, a coworker, or a family member. (It’s not just romantic relationships that can become toxic.)
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January 12, 2016, by NCI Staff The genes PDGFRA and FIP1L1 are normally confined to separate loop domains (A) and rarely interact, but they can become closely associated (B) in tumors with IDH mutations. Credit: Broad Communications / Lauren Solomon Researchers studying brain tumors have identified a previously unknown genetic mechanism that may contribute to
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January 6, 2016, by NCI Staff The FDA recently approved three new drugs to treat multiple myeloma. One of the drugs is the first approved cancer therapy to target the CD38 protein (pictured). Credit: Wikimedia Commons / Emw, CC-BY-SA-3.0 The Food and Drug Administration (FDA) has approved three new drugs for the treatment of multiple myeloma
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December 28, 2015, by NCI Staff Last month, the FDA approved two drugs that inhibit the activity of the epidermal growth factor receptor, or EGFR, for the treatment of patients with advanced lung cancer. Credit: Wikimedia Commons Last month, the Food and Drug Administration (FDA) approved two targeted therapies for patients with advanced non-small cell
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