Aging

Population-based data on human biological growth and development processes are fundamental for assessing the health status of a community. For many populations in rural Africa, birth registry and eliciting date of birth are still challenges. Data on uncompromised development and growth variation in most developing populations are surprisingly lacking, and researchers typically compare growth in
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Mushrooms may contain unusually high amounts of two antioxidants that some scientists suggest could help fight aging and bolster health, according to a team of Penn State researchers. In a study, researchers found that mushrooms have high amounts of the ergothioneine and glutathione, both important antioxidants, said Robert Beelman, professor emeritus of food science and
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Treatment with a neuroprotective compound that saves brain cells from dying also prevents the development of depression-like behavior and the later onset of memory and learning problems in a rat model of Alzheimer’s disease. Although the treatment protects the animals from Alzheimer’s-type symptoms, it does not alter the buildup of amyloid plaques and neurofibrillary tangles
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Understanding the factors that control aging has been one of humanity’s endless pursuits, from the mystical fountain of youth to practical healthful regimens to prolong life expectancy. A team of scientists at the University of California San Diego has helped decipher the dynamics that control how our cells age, and with it implications for extending
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Researchers determine whether there is an association between aggressive treatment of hypertension and cognition function. Despite the relationship between hypertension and cognition being well established, recent concerns have arisen surrounding the treatment of hypertension. This concern is due to suspicions that more aggressive hypertension treatment, particularly in the elderly, may actually be linked to adverse
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Researchers at Lund University in Sweden have for the first time convincingly shown where in the brain the earliest signs of Alzheimer’s occur. The discovery could potentially become significant to future Alzheimer’s research while contributing to improved diagnostics. In Alzheimer’s, the initial changes in the brain occur through retention of the protein, ?-amyloid (beta-amyloid). The
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In hopes to find a new treatment for Alzheimer’s, researchers determine if toxic tau tangles are the primary drivers responsible for the disease. The two pathological hallmarks of the devastating neurodegenerative disorder, Alzheimer’s disease, are amyloid plaques and tau protein tangles. Amyloid plaques and tau protein tangles are two brain abnormalities of Alzheimer’s disease. Amyloid
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Alzheimer’s disease, the leading cause of dementia, has long been assumed to originate in the brain. But research from the University of British Columbia and Chinese scientists indicates that it could be triggered by breakdowns elsewhere in the body. The findings, published today in Molecular Psychiatry, offer hope that future drug therapies might be able
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A major study by researchers at William & Mary’s Virginia Institute of Marine Science shows that many diverse species of Chesapeake Bay fishes — whether they eat zooplankton, other fishes, or bottom-dwelling invertebrates — exhibit similar year-to-year trends in a common measure of their overall health. VIMS Professor Rob Latour says the study provides “useful
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A recent meta-analysis investigates whether sex, age, and a particular genotype are associated with a greater risk of developing Alzheimer’s disease. Alzheimer’s Disease (AD) is a chronic neurodegenerative condition, characterized by cognitive deficits in memory, thinking, and behaviour. Research has shown that different environmental, genetic, and socioeconomic cues can increase the risk of developing Alzheimer’s
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The relationship between memory and time has been studied extensively but is still poorly understood. A new study assessed memory and time deficits in Alzheimer’s disease (AD) patients in their home environments. It is widely accepted that as time passes, the ability to recall events and specific information declines. Episodic memory is the type of
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A recent analysis of geriatric patients hospitalized through emergency departments shows that proper geriatric assessments of older patients may reduce admission rates. A recent article published in Age and Ageing by the Oxford University Press reviewed the evidence behind performing comprehensive geriatric assessments (CGA) for more elderly patients that present at the emergency department. The
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In a recent study, researchers sought to identify proteins important for the anti-neural plasticity effects of histone deacetylase 2 (Hdac2) in Alzheimer’s disease. How Cells Control Gene Activity Acetylation is one method by which cells control gene activity by the addition or removal of acetyl groups. Acetylation is performed by enzymes called acetyltransferases on histone
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Hydration health issues in the elderly have significant economic effects and while most elderly people recognize the importance of proper hydration, there may be limited health literacy including knowledge of signs and symptoms and health consequences of improper hydration. Dehydration is caused by excess fluid loss from the body and can lead to serious health
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Medication administration and management is a real problem in patients suffering from medical conditions associated with cognitive deficits. A recent study examined the experience of family members as they help take care of elder family members with Alzheimer’s disease. Compliance is an ongoing issue in medicine, particularly for elderly patients with medical conditions that cause
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In a 2017 study, researchers examined the relationship between rare gene variants and early-onset Alzheimer’s disease risk. Variants in a number of genes were identified, including PSD2, TCIRG1, and RIN3 – genes important to endolysosomal function. Mutations in a number of key genes have been implicated in the development of 5-10% of early-onset Alzheimer’s disease
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Tau proteins might be associated with dementia (including Alzheimer’s disease) as well as mild cognitive impairment and cognitive decline. The current study found that higher levels of total tau in blood plasma were significantly associated with cognitive decline. Dementia represents a broad category of neurological diseases that cause gradual cognitive decline over time. The most
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Recently, the end of life care experienced by older adult individuals has sparked interest and observations have been made to identify the potential risk factors for aggressive care along with an evaluation of the cost. This highlights the need to keep families informed about what to expect when an older adult in their midst has
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Research examines the prevalence of abuse in older adults globally and in turn highlight the risk and need for increased protection services in this regard. Elderly abuse continues to be a growing problem. In 2015 there were an estimated 901 million older adults, or adults over the age of 65, globally. Psychological abuse is the
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A recent article, published in The American Journal of Clinical Nutrition, investigates how the metabolism of eicosapentaenoic acid (EPA) and arachidonic acid (AA) changes with age. There are significant metabolic and biological changes that occur with progressing age. These changes must be taken into consideration to maintain a healthy and balanced nutritional intake. For instance,
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