Aging

Recent studies have identified an association between the height of an individual and their risk of various age-related diseases. Researchers investigated the relationship between adult height and healthy aging in a study population of female nurses and found that height has effects on healthy aging; they also found this association could be modified through dietary
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A cohort study in Japan investigated the relationship between eating citrus fruits and developing dementia later in life. The authors controlled for a number of confounding factors, and found that the consumption of citrus is linked with lower incidence of dementia. Neurodegeneration leading to loss of cognitive function, generally referred to as dementia, is a
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Diagnosis of mild-cognitive impairment (MCI) and, in many cases, the subsequent incident dementia in the elderly has proven to be difficult with current methods such as cerebrospinal fluid biomarker analysis. An article in JAMA Neurology discusses how a dual-task gait performance paradigm was used successfully as a diagnostic marker of progression to dementia in elderly
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Researchers out of France and Monaco recently finished one of the longest and largest studies on Alzheimer’s disease. The study focused on using multidomain lifestyle intervention with Omega 3 supplementation for Alzheimer’s patients. The results, unfortunately, were insignificant, but do provide swaths of new data and show potential for new treatment approaches that are less
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Within the health community, the use of medical marijuana is controversial. Recently, a German-Israeli research team found evidence that small, controlled amounts of the active ingredient in marijuana, THC, improved cognitive function and memory in older mice. Dementia is a general term used to describe cognitive decline in older people caused by damage to the
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Music therapy is a promising tool in the treatment of Alzheimer’s and other neurodegenerative diseases. A new course offered by Ithaca College and a student organization provide music therapy to local nursing home residents. With so much enthusiasm for the course and organization, Ithaca College may start offering a Music as Medicine major or minor.
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A recently published study investigated whether low-density lipoprotein (LDL) cholesterol may have a causal relationship with Alzheimer’s disease, Parkinson’s disease, and dementia. Cholesterol serves as a component in the myelin sheath, a protective layer for neurons. Patients taking drugs that lower levels of cholesterol, such as statins, may be at risk of developing neurological conditions
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Alzheimer’s disease is mainly caused by amyloid and neurodegeneration. A recent study shows several factors that may protect against the two main causes. The two main factors most acknowledged to contribute to Alzheimer’s disease (AD) are amyloid, — when protein build up wreaks havoc in neurons, — and neurodegeneration. The most widely accepted model for
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Older adults who are hospitalized are at an increased risk of delirium, an impaired mental state with acute onset, which may increase their risk of in-hospital and post-discharge mortality. A recent study published in PLoS Medicine investigated whether mortality risk is greater among hospitalized older adults with delirium superimposed on dementia. Delirium is characterized by
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The endopeptidase delta-secretase is partly responsible for mediating the accumulation of beta-amyloid plaques and tau protein aggregates: two prime suspects in the pathogenesis of Alzheimer’s disease. A new study reports an orally bioactive and highly selective small molecule inhibitor of delta-secretase that can prevent the accumulation of aggregated proteins and improve cognition in mouse models
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There is a demographic gap between babies born with HIV in the past and recently. Older patients are at an increased risk for viral load in blood, immunosuppression, more severe clinical events, and mortality compared to those born recently due to advances in treatments starting at an earlier age. Current antiretroviral (ARV) and combination antiretroviral
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Episodes of dementia symptomatic of Alzheimer’s disease (AD) often require treatment with anxiolytics such as benzodiazepines (BZ). This treatment has previously been suggested to be associated with pneumonia as an unexpected side effect, although the evidence is contradictory. In a recent retrospective study, a group of Finland practitioners provide evidence supporting that suggests BZ treatment
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Frailty is a risk factor that particularly affects the elderly population, which is predominantly female. Nutrition has been identified as a key contributor to frailty, and with diet modification, a potential therapeutic target. With advances in science and medicine, our population is living to ages that we have not seen before. This comes with a
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An ex vivo and a clinical trial were conducted by researchers from France to determine the efficacy of glucosamine sulphate in preventing skin aging. Glucosamine sulphate is a naturally occurring compound in the body, aiding in the production of different substances such as hyaluronic acid, heparan sulfate, and glycosaminoglycans. Glycosaminoglycans, together with elastin and collagen,
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Researchers in India report that yoga postures, breathing disciplines and meditation may be the key to prolonging that proverbial fountain of youth. Biomarkers found in human blood samples drawn during a clinical trial showed the anti-aging benefits of practicing these ancient holistic practices. In the Yoga and Meditation Based Lifestyle Intervention (YMLI) clinical trial, scientists
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