Cancer

Cancer immunotherapies are ushering in an era of new promise and, it is now clear, new problems. Recognition of an increasing number of unique and unexpected adverse events — sometimes appearing long after treatment ends — prompted the Society for Immunotherapy of Cancer to form a Toxicity Management Working Group and to put out a
0 Comments
Biologic treatments for cancer, such as immunotherapy, are a growing field of drug research and development. These new treatments have had a remarkable effect on the lives of people with cancer, but they often come with high price tags. These new treatments have had a remarkable effect on the lives of people with cancer, but
0 Comments
February 14, 2018, by NCI Staff Tumors in desmoplastic melanoma, a rare form of the skin cancer melanoma, often contain thin, elongated cells called spindle cells that are surrounded by fibrous tissue. Credit: Dermatol Res Pract 2009. doi: 10.1155/2009/679010. Creative Commons A new study suggests that patients with a rare form of melanoma, called desmoplastic
0 Comments
Faster genomic sequencing and other tools are hastening the development of new diagnostic and prognostic tools for prostate cancer. Yet determining how best to develop, translate, and deploy them to the clinic will be a methodical process, reported researchers at the 2018 Genitourinary (GU) Cancers Symposium in San Francisco, California. “With an improving understanding of
0 Comments
February 13, 2018, by NCI Staff Credit: National Human Genome Research Institute Targeting the body’s biological clock may be a potential strategy for treating cancer, a new study shows. Two compounds that target components of the circadian clock killed several types of cancer cells in the lab and slowed the growth of brain tumors in
0 Comments
February 12, 2018 Researchers evaluated whether dual HER2 inhibition with trastuzumab and pertuzumab plus metronomic cyclophosphamide is superior to dual HER2 inhibition alone. Dual HER2 blockade with metronomic chemotherapy may be effective for treating elderly patients with HER2-positive metastatic breast cancer, according to a study published
0 Comments
As more data are published, novel therapies and regimens approved, and indications expanded, a shift toward multidisciplinary care is inevitable for the treatment of locally advanced and metastatic renal cell carcinoma (RCC). “Multidisciplinary care is being integrated even more now that our treatments are expanding in each of the disease presentations,” Rana R. McKay, MD,
0 Comments
February 09, 2018 This article originally appeared on Renal and Urology News. In separate studies, apalutamide, an investigational agent, and enzalutamide prolonged metastasis-free survival in men with non-metastatic castration-resistant prostate cancer. SAN FRANCISCO—Treatment of non-metastatic castration-resistant prostate cancer (CRPC) with apalutamide or enzalutamide, both orally
0 Comments
February 9, 2018, by NCI Staff Researchers are developing tumor-targeting viruses, like this engineered poliovirus, as potential cancer treatments. Credit: Duke Cancer Institute For more than a century, doctors have been interested in using viruses to treat cancer, and in recent years a small but growing number of patients have begun to benefit from this
0 Comments
There is strong evidence that increased physical activity lowers the risk for several cancers, including colon cancer and breast cancer, and further that physical activity is beneficial for improving quality of life and delaying cancer recurrence or progression.1 A recent review published in the British Journal of Sports Medicine indicated that regular exercise might also
0 Comments
When Leland Dunwoodie, an undergraduate researcher in biochemistry, approached his PI about wanting to start research on “some human stuff” in the spring of 2016, he didn’t imagine it would lead to the discovery of 22 genes that are implicated in glioblastoma, the most aggressive type of brain cancer. “I definitely didn’t come to Clemson
0 Comments
Chemicals that attract specialised immune cells toward tumours could be used to develop better immunotherapies for cancer patients, according to new research published in Cell. Scientists at the Francis Crick Institute have discovered that immune cells called Natural Killer cells accumulate in tumours and release chemicals that attract specialised dendritic cells (cDC1) — white blood
0 Comments
February 8, 2018, by NCI Staff An endoscopic ultrasound of a neuroendocrine tumor (NET) in the upper gastrointestinal tract (duodenum). Credit: BMC Gastroenterol 2011. doi: 10.1186/1471-230X-11-67 CC 2.0. People with certain cancerous neuroendocrine tumors (NETs) affecting the digestive tract now have a new treatment option. On January 29, the Food and Drug Administration (FDA) approved
0 Comments
Lignans are phenolic compounds found frequently in fiber-rich plants, such as flax (Linum usitatissimum). Flax is particularly high in the lignans secoisolariciresinol diglucoside (SDG), SECO, and matairesinol. SDG is converted in the human colon by bacteria into the mammalian lignans enterodiol and enterolactone. Flaxseed, its lignans, and enterolactone have been studied for anticancer activity in
0 Comments
Valérie Tettinek worked at a senior executive level for major corporations for nearly 2 decades. Now she specializes in consulting, training, and coaching, particularly in making positive changes in health care and cancer care. I was 34 years old when I was diagnosed with synovial sarcoma and told that I had 6 months to live.
0 Comments
A single protein building block commonly found in food may hold a key to preventing the spread of an often-deadly type of breast cancer, according to a new multicenter study published today in the medical journal Nature. Investigators found that by limiting an amino acid called asparagine in laboratory mice with triple-negative breast cancer, they
0 Comments