Clinical Trials & Research

Diabetes is a common metabolic disorder. Researchers recently examined if diabetes is also associated with higher cancer incidence. Diabetes is a metabolic disorder that is estimated to affect 7% of Canadians (approximately 2.1 million) according to Statistics Canada. Diabetics suffer from uncontrolled blood glucose levels due to complications releasing insulin, a blood glucose regulating hormone.
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A recent study assessed the association between chronic conditions, physical multi-morbidity, and sedentary behaviour among adults in six countries. Sedentary behaviour is associated with a wide range of deleterious outcomes such as diabetes, stroke, and premature mortality, irrespective of a person’s physical activity levels. There have been no studies that are nationally representative, multi-national, or
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(1204) Egyptian rabbi and physician Maimonides passes away. In his writings, he described a number of topics including asthma, diabetes, hepatitis, and encouraged moderation and a healthy lifestyle. (1905) Austrian-French novelist, essayist and psychologist Manès Sperber is born. He wrote a number of books on psychology and development. (1909) German/Dutch novelist,
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As reported in Science Magazine, an American research institute recently launched an initiative to share data from live human brain cells. As technological advancements have been made in the field of biology, scientists have been, to a greater extent, able to study the specifics of the human body. An increasingly common technique is to fully
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Current guidelines in the United States recommend cervical screening until 65 years. Researchers investigate the effectiveness of screening in older women. The high rate of cervical cancer in older women continues to be a concern for countries that have long-established cervical screening practices. By these measures, countries have seen a significant reduction in cervical cancer
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Myth: Prostate cancer screening reduces an individual’s mortality rate. Truth: This is false. Studies show that increased screenings for prostate cancer could lead to overly aggressive treatments, financial concerns, and reduced patient quality of life. Furthermore, prostate cancer typically goes unnoticed as the onset of prostate cancer rarely displays symptoms. Some
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Myth: Prostate cancer screening reduces one’s mortality rate. Truth: This is false. Studies show that increased screenings for prostate cancer could lead to overly aggressive treatments, financial concerns, and reduced patient quality of life. Furthermore, prostate cancer typically goes unnoticed as the onset of prostate cancer rarely displays symptoms. Some regular
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A randomized trial investigated the effects of brain surgery on the risk of recurrent seizures in children with drug-resistant epilepsy. Drug-resistant epilepsy carries significant health burdens. In addition to the risk of recurrent seizures, young people with this condition are at a higher risk of poor intellectual and psychosocial development. A common treatment for this
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A recent study sheds new light on the genetic basis of alcohol dependence and major depression, which could help develop new treatments for these conditions. Although the comorbidity of alcohol dependence and major depression is recognized, the underlying basis of their co-occurrence is not well understood. Studies indicate that alcohol dependence increases the risk of
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A recent article discusses a landmark program that involves DNA screening of healthy individuals to identify genetic variants associated with disease. The development of technologies that allow for the rapid and affordable sequencing of entire human genomes has accelerated medical research and is expected to make actionable genetic information available to health service providers as
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Researchers find that new CRISPR genome editing modifications increase the precision and safety for treating certain genetic diseases. Since its debut in 2012, CRISPR genome editing has been a transformative tool for researchers to solve complex genetic disorders. CRISPR, which stands for Clustered Regularly Interspaced Short Palindromic Repeats, is a genome editor that acts as
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In a new meta-analysis, researchers test whether circadian rhythms affect weight by examining the relationship between portion sizes and weight loss. Many people struggle to maintain a healthy weight. Diets and weight loss programs abound and most of them focus on cutting the number of calories people consume. However, many who do lose weight struggle
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Le malattie infiammatorie croniche intestinali sono condizioni croniche, probabilmente generate da diverse cause. Un recente studio ne ha esaminato i fattori ambientali. Le malattie infiammatorie croniche intestinali (MICI), come la malattia di Crohn’s e la colite ulcerosa, sono condizioni recidivanti-remittenti causati da diversi ipotetici fattori. Negli ultimi anni, sì è osservato un aumento dell’incidenza e
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Les chercheurs chinois se pencher sur les effets potentiels des compléments alimentaires à base de grenade sur la glycémie et la sensibilité à l’insuline. Le diabète sucré est un problème de santé publique grave qui a affecté 336 millions de personnes dans le monde entier en 2014. Cette évaluation devrait augmenter à 552 millions de
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饮食中的添加糖一直以来口碑不佳,然而,一项研究通过揭示D-甘露糖和糖尿病间的关系来论述添加糖是否为健康带来益处。 糖具有产生和储存能量之功效,同时有助于维持对机体细胞的调节,因而在机体中发挥重要作用。然而,快速Google搜索“添加糖”词条会得到大量有关在饮食中添加糖的害处的网络链接。确实如此,添加糖中不含任何微量营养素,却对人体肝脏造成损害,还会导致机体产生胰岛素抵抗,诱发2型糖尿病及肥胖。考虑到添加糖的致病作用,营养学专家提倡削减添加糖的使用,而应该更多使用诸如来自植物和水果中的天然糖。 但是,一项由 Wanjun Chen博士主持的新近研究提示上述规则可能存在一种例外。研究小组在自身免疫性糖尿病小鼠模型上的研究显示,一种源自植物和水果的葡萄糖异构体-D-甘露糖对1型糖尿病和哮喘性肺炎有抑制功效。研究中,科研人员在实验模型小鼠的饮水中添加小剂量D-甘露糖,这一处理在小鼠出现糖尿病症状前进行。很明显,添加D-甘露糖能有效阻止小鼠罹患糖尿病,而实验对照组小鼠(正常饮水)则不能幸免。此外,饮水中添加D-甘露糖也可阻止哮喘鼠肺部呼吸道炎症的发生。 该研究小组进一步发现,D-甘露糖能促进机体产生调节性T细胞,该类细胞具有调控免疫系统并阻止自身免疫性疾病发生之功效,因此,D-甘露糖可抑制实验鼠的炎症反应,阻止其罹患诸如糖尿病和哮喘等自身免疫性疾病。重要的是,研究表明,即使添加对人体肝脏无毒性的生理性小剂量D-甘露糖也足以刺激机体产生调节性T细胞。上述研究结果近期已在Cell and Bioscience期刊上进行了论述。 综上,该项研究发现D-甘露糖是一种可能成为安全的饮食添加剂的“健康”或“有益”糖。有关D-甘露糖与糖尿病间关系的研究发现提示,D-甘露糖可用于一系列过敏和免疫性疾病的防治,而不会对人体健康造成损害,尽管如此,正如上述研究所指出的,仍需开展临床试验对D-甘露糖的安全性及机体的耐受进行测试确认。   作者: Neeti Vashi, BSc译者: Mingfa Li, Ph.D, M.D 参考文献: Shi Y and Yin D. A good sugar, D-mannose, suppresses autoimmune diabetes. Cell Biosci. 25 September 2017 Previous articleDo Statins for High Cholesterol Decrease Deaths from Heart
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La pérdida de pesa es importante para esos individuos en el riesgo de diabetes, pero cual dieta es la mejor? Los investigadores determinaron recientemente la dieta más efectiva para la perdida de pesa en diabetes. Las diabetes es un problema de todo el mundo y mucha investigación fue hecha en la prevención, el manejo, y
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There has been growing interest in the health benefits of nature therapy. Researchers recently reviewed the scientific evidence for these benefits. Poets and other writers have long expounded the spiritual and health benefits of nature. Now, there is increasing interest from clinical and scientific circles in whether there are quantifiable health benefits to going outdoors,
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A research group evaluated whether higher e-cigarette nicotine levels contribute to increased frequency and intensity of cigarette smoking and vaping. Last year, a worrisome 11% of American 10th-grade students reported using e-cigarettes (vaping) in the past month. Prior research has proven that teens who vape are at a higher risk of starting and consequently progressing
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Individual taste preferences shape food intake. A recent study tested whether taste sensitivity for complex carbs shaped taste preferences and food intake. Many adults struggle with their weight, in part because modern diets are highly dependent on energy- and carbohydrate-rich foods like bread, pasta, and soda. However, different people perceive simple carbohydrates (simple sugars) and
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In a recently published review, researchers summarize the effects of paternal obesity on male fertility — specifically sperm quality and progeny health. Obesity, defined as the excessive accumulation of adipose tissue, is a well-established risk factor for many pathologies, including hypertension, kidney and cardiovascular disease, and type II diabetes. Recent studies have shown that obesity
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